Our Science

Mechanisms of Action of an Investigational New Freeze Dried Platelet-Derived Hemostatic product

Benjamin J. Kuhn, Ana Swanson, Arjun S. Cherupalla, G. Michael Fitzpatrick, W. Allan Alexander, Keith A. Moskowitz

Journal of Thrombosis and Haemostasis

March 30, 2024

In Vitro Treatment of Extracorporeal Membrane Oxygenation Coagulopathy with Recombinant von Willebrand Factor or Lyophilized Platelets

Michael Mazzeffi, Alberto Gonzalez-Almada, Richard Wargowsky, Lucas Ting, Keith Moskowitz, Max Hockstein, Danielle Davison, Jerrold H. Levy, Kenichi A. Tanaka

Journal of Cardiothoracic and Vascular Anesthesia

May 13, 2023

Freeze-dried Platelets Are a Promising Alternative in Bleeding Thrombocytopenic Patients with Hematological Malignancies

M. Ohanian, J. Cancelas, R. Davenport, V. Pullarkat, T. Hervig, C. Broome, K. Marek, M. Kelly, Z. Gul, N. Ruggs, S. Nestheide, B. Kinne, Z. Szczepiorkowski, H. Kantarjian, J. Pehta, R. Biehl, A. Yu, F. Aung, B. Antebi, M. Fitzpatrick

American Journal of Hematology

November 8, 2021

Freeze-dried platelets promote clot formation, attenuate endothelial cell permeability, and decrease pulmonary vascular leak in a murine model of hemorrhagic shock

A. Trivedi, D. Potter, B. Miyazawa, M. Lin, L. Vivona, M. Khakoo, B. Antebi, A. Lee, B. Ishler, M. Dickerson, R. Kozar, M. Schreiber, J. Holcomb, G. Fitzpatrick, S. Pati

The Journal of Trauma and Acute Care Surgery

February 1, 2021

Lyophilized platelets sersus cryopreserved platelets for management of bleeding in thrombocytopenic dogs: A multicenter randomized clinical trial

R. Goggs, B. Brainard, D. LeVine, J. Calabro, K. Harrell, T. Mills, R. Stone, B. Davidson, C. Lacovette, L. Harris, J. Gicking, M. Aslanian, A. Ziegler, B. Fulcher, T. Lightfoot, M. Miller, J. Lotfus, R. Walton, A. Blong, K. Kishbaugh, A. Hale

Journal of Veterinary Internal Medicine

October 5, 2020

Platelets: Frozen and Freeze-Dried Current Products in Development and Regulatory Licensing Challenges

Pidcoke H., Kelly K., Fitzpatrick G.M., Dumont L.J.

Damage Control Resuscitation

January 1, 2020

Evaluation of a Lyophilized platelet-derived hemostatic product

J. Bynum, M. Meledeo, G. Peltier, C. McIntosh, A. Taylor, R. Montgomery, K. Reddoch-Cardenas, T. Getz, M. Fitzpatrick, A. Cap

April 1, 2019

Novel platelet products under development for the treatment of thrombocytopenia or acute hemorrhage

Michael Fitzpatrick G.

Transfusion and Apheresis Science: Official Journal of the World Apheresis Association: Official Journal of the European Society for Haemapheresis

February 1, 2019

Safety evaluation of a lyophilized platelet-derived hemostatic product

Jeffrey Barroso; Barbara Osborne; Gayle Teramura; Esther Pellham; Michael Fitzpatrick; Ruth Biehl; Anna Yu; Joan Pehta; Sherrill J. Slichter

Transfusion

December 1, 2018

Dried Platelets in a Swine Model of Liver Injury

Kenji Inaba; Galinos Barmparas; Peter Rhee; Bernardino C. Branco; Michael Fitzpatrick; Obi T. Okoye; Demetrios Demetriades

Shock

May 1, 2014

Lyophilised reconstituted human platelets increase thrombus formation in a clinical ex vivo model of deep arterial injury

G. Michael Fitzpatrick; Richard Cliff; Narendra Tandon

Transfusion

January 1, 2013

Thrombosomes: a platelet-derived hemostatic agent for control of noncompressible hemorrhage

G. Michael Fitzpatrick; Richard Cliff; Narendra Tandon

Transfusion

January 1, 2013

Wound-healing properties of trehalose-stabilized freeze-dried outdated platelets

Ruth Sum; Sarah Hager; Giorgio Pietramaggiori; Dennis P. Orgill; Josh Dee; Alan Rudolph; Cindy Orser; G. Michael Fitzpatrick; David Ho

Transfusion

April 1, 2007

Trehalose lyophilized platelets for wound healing

Giorgio Pietramaggiori, MD; Arja Kaipainen, MD, PhD; David Ho, PhD; Cindy Orser, PhD; Walter Pebley, PE; Alan Rudolph, PhD, MBA; Dennis P. Orgill, MD, PhD

Wound Repair and Regeneration

March 1, 2007

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